Chelsea is a neighborhood on the West Side of the borough of Manhattan in New York City. The district's boundaries are roughly 14th Street to the south, the Hudson River and West Street to the west, and Sixth Avenue to the east, with its northern boundary variously described as near the upper 20’s or 34th Street, the next major crosstown street to the north. To the northwest of Chelsea is the neighborhood of Hell's Kitchen, as well as Hudson Yards; to the northeast are the Garment District and the remainder of Midtown South; to the east are NoMad and the Flatiron District; to the southwest is the Meatpacking District; and to the south and southeast are the West Village and the remainder of Greenwich Village. Chelsea is named after the Royal Hospital Chelsea in London, England.

Chelsea is part of Manhattan Community District 4 and its primary ZIP Codes are 10001 and 10011. It is patrolled by the 10th Precinct of the New York City Police Department.